Home of the farrp allergen protein database
WWF and Kimberly-Clark announce new global commitment to responsible forestry. China air pollution hits record levels but relief may be close at hand - for some. OxyPharm disinfection units now available through rental serv ice. This persistant infection is clinically very important as it causes permanent failure of lungs [ 96 , 97 ]. Study highlights need for more knowledge about green cleaning programmes in hospitals.
온라인 진료예약 서비스 안내
The Scientist , 30, RNA epigenetics — chemical messages for posttranscriptional gene regulation. Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer. Detecting hepatocellular carcinoma in blood. Structural insight into substrate preference for TET-mediated oxidation.
Chemical decaging in living systems. Bacterial infection remodels the DNA methylation landscape of human dendritic cells. Methods , 12, Cell , 59, Efficient and quantitative high-throughput tRNA sequencing. Methods , 12 , RNA N 6 -methyladenosine methylation in post-transcriptional gene expression regulation.
Widespread occurrence of N 6 -methyladenosine in bacterial mRNA. Decoding the transcriptome and DNA methylome of human primordial germ cells. N 6 -methyldeoxyadenosine marks active transcription start sites in Chlamydomonas. N 6 -methyladenine DNA modification in Drosophila. Preparation of human nuclear RNA m6A methyltransferases and demethylases and biochemical characterization of their catalytic activity. Fate by RNA methylation: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth.
Cancer Cell , 27 , Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics. Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling. Methods , 72 , Pseudouridine in a new era of RNA modifications. Visualizing a protein's sugars. TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator. Unique features of the m 6 A methylome in Arabidopsis thaliana. UO Uptake by Proteins: Dynamic RNA modifications in posttranscriptional regulation.
Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells. Genomics , , Small , 10 , Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth. Synthesis of a FTO inhibitor with anticonvulsant activity. Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain.
Dynamics of spontaneous flipping of a mismatched base in DNA duplex. The dynamics of DNA methylation fidelity during mouse embryonic stem cell self-renewal and differentiation. Reading RNA methylation codes through methyl-specific binding proteins.
Programming and inheritance of parental DNA methylomes in mammals. Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa. Gene expression regulation mediated through reversible m 6 A RNA methylation. Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2. Nucleic acid oxidation in DNA damage repair and epigenetics.
A protein engineered to bind uranyl selectively and with femtomolar affinity. N 6-methyladenosine-dependent regulation of messenger RNA stability. The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli.
Understanding variation in transcription factor binding by modeling transcription factor genome-epigenome interactions. Probing subcellular organic hydroperoxide formation via a genetically encoded ratiometric and reversible fluorescent indicator. Integrative Biology , 5 , A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells. Global epigenomic reconfiguration during mammalian brain development.
Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis. Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. ALKBH4-dependent demethylation of actin regulates actomyosin dynamics. Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos.
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Sprouts of RNA epigenetics: The discovery of mammalian RNA demethylases. Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidation. Cold Spring Harb Perspect Biol. Reversible RNA adenosine methylation in biological regulation. Trends in Genetics , 29, Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
Cancer Cell , 22 , Mapping recently identified nucleotide variants in the genome and transcriptome. Nucleic acid modifications with epigenetic significance. Current Opinion in Chemical Biology , Balance of DNA methylation and demethylation in cancer development. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum.
The oxidation-sensing regulator MosR is a new redox dependent transcription factor in Mycobacterium tuberculosis. A selective fluorescent probe for carbon monoxide imaging in living cells.
Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy. Tetrahedron , 68 , Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus. Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA.
Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response. Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. Heterologous expression and purification of Arabidopsis thaliana VIM1 protein: In vitro evidence for its inability to recognize hydroxymethylcytosine, a rare base in Arabidopsis DNA.
Differential function of lip residues in the mechanism and biology of an anthrax hemophore. Expression of multidrug resistance efflux pump gene norA is iron-responsive in Staphylococcus aureus. Binding of ReO 4 - with an engineered MoO 4 2- -binding protein: Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development.
The hunt for 5-hydroxymethylcytosine: Selective fluorescent probes for live-cell monitoring of sulphide. Targeting MgrA-mediated virulence regulation in Staphylococcus aureus. Selective recognition of americium by peptide-based reagents. Science , , Epub Feb Emergence of fluoroquinolone-resistant Stenotrophomonas maltophilia in blood isolates causing bacteremia: Epub Oct Epub Jul The cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus blood isolates: Epub Jun Int J Antimicrob Agents.
Epub Nov 3. Epub Dec 1. A new causative bacteria of infective endocarditis, Bergeyella cardium sp nov. Clinical features and risk factors for development of Bacillus bacteremia among adult patients with cancer: Anti-anaerobic coverage is not necessary for Klebsiella pneumoniae liver abscess: Outcome of culture-negative pyogenic vertebral osteomyelitis: Epub Aug 1.
Extended-spectrum cephalosporins and the inoculum effect in tests with CTX-M-type extended-spectrum beta-lactamase-producing Escherichia coli: Scand J Infect Dis. Epub Apr 1. Epub Sep 6. Risk factors for levofloxacin-nonsusceptible Streptococcus pneumoniae in community-acquired pneumococcal pneumonia: Mortality of Community-Acquired Pneumonia in Korea: Epub Jul 3.
J Korean Med Sci.? Epub May 2. Epub Jan 6. Is adjunctive corticosteroid beneficial in pneumococcal meningitis in a region with high rates of resistance to penicillin and ceftriaxone Moon SY1 1 ,? Prevalence and molecular characterization of serotype K1 Klebsiella pneumoniae strains from various clinical specimen sources in 11 Asian countries Chung DR 1 ,? Epub Jul 8. Epub Jan 9.
Impact of discordant empirical therapy on outcome of community-acquired bacteremic acute pyelonephritis Lee SS1 1 ,? Epub Apr 8.