The powder is usually mixed with water, milk or fruit juice and is generally consumed immediately before and after exercising or in place of a meal. It may not even feel like you are dieting. The Journal of Clinical Endocrinology and Metabolism. In conclusion, HMB treatment clearly appears to be a safe potent strategy against sarcopenia, and more generally against muscle wasting, because HMB improves muscle mass, muscle strength, and physical performance. Proceedings of the Royal Society B. Each meal or shake from Medifast provides about calories. Although initially available over the counter, their purchase was made illegal without a prescription in the US in , and they hold similar status in many other countries.
Of the 23 trials they identified, 12 were methodologically sound enough to include in their analysis. The analysis revealed that some statistically significant weight loss occurred, but the magnitude of the effect is small and the clinical relevance is uncertain. They also found that gastrointestinal adverse events were twice as likely in the hydroxycitric acid group as in the placebo group.
When you are considering the potential benefits of products look for meta-analysis studies that take in all the sound research available.